Among Paul's assistants at Rome were many of his former companions and fellow workers. Luke, "the beloved physician," who had attended him on the journey to Jerusalem, through the two years' imprisonment at Caesarea, and upon his perilous voyage to Rome, was with him still. 455 Timothy also ministered to his comfort. Tychicus, "a beloved brother, and a faithful minister and fellow servant in the Lord," stood nobly by the apostle. Demas and Mark were also with him. Aristarchus and Epaphras were his "fellow prisoners." Colossians 4:7-14.

Blandt Paulus medhjælpere i Rom fandtes mange af hans tidligere fæller og medarbejdere. "Lægen Lukas, den elskede," som havde taget sig af ham på rejsen til Jerusalem, under de to års fængsling i Kæsarea og under den farlige rejse til Rom, var stadig hos ham. Også Timoteus sørgede for ham. Tykikus, "den elskede broder og trofaste hjælper og medtjener i Herren " blev tappert hos apostlen. Også Demas og Markus var hos ham. Aristarkus og Epafras var "hans medfanger." Kol. 4,7-14.